Regeneron Pharmaceuticals, Inc.
Stabilized Formulations Containing Anti-Interleukin-4 Receptor (IL-4R) Antibodies

Abstract:

The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-4 receptor (hIL-4R). The formulations may contain, in addition to an anti-hIL-4R antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.