Regeneron Pharmaceuticals, Inc.
IMMUNOGLOBULIN PROTEINS THAT BIND TO NPR1 AGONISTS
Last updated:
Abstract:
The present disclosure provides novel immunoglobulin proteins that bind to a human natriuretic peptide receptor 1 (NPR1) agonist, preferably an anti-NPR1 antibody. In certain embodiments, the proteins of the disclosure comprise at least one immunoglobulin variable domain that binds to an anti-NPR1 antibody. In certain embodiments, the proteins of the disclosure are useful in blocking and/or reversing the effect of an administered anti-NPR1 antibody. In certain embodiments, the antigen-binding proteins are useful for effective management of blood pressure and hemodynamics in humans.
Status:
Application
Type:
Utility
Filling date:
17 Dec 2021
Issue date:
23 Jun 2022