Revance Therapeutics, Inc.
Compositions and methods for topical application and transdermal delivery of botulinum toxins
Last updated:
Abstract:
Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.
Status:
Grant
Type:
Utility
Filling date:
24 Sep 2018
Issue date:
18 Aug 2020