Revance Therapeutics, Inc.
BOTULINUM TOXIN FORMULATIONS AND METHODS OF USE THEREOF IN PLANTAR FASCITIS WITH EXTENDED DURATION OF EFFECT

Abstract:

This invention relates to injectable and transdermal compositions comprising botulinum toxin and their methods of use in administering botulinum toxin to treat or manage plantar fasciitis, a disorder related thereto, or a symptom thereof. The injectable and transdermal compositions and methods in which these compositions are used provide advantageous treatments which result in fast onset, higher responder rates, and/or long duration of effect, for example, a duration of effect for over six months and/or a reduction in plantar fasciitis pain by at least 50% maintained through week 8 following treatment. The topical compositions and methods provide desirable, less painful, treatment alternatives.