Sage Therapeutics, Inc.
19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF

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Abstract:

Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): ##STR00001## and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.

Status:
Application
Type:

Utility

Filling date:

9 Oct 2020

Issue date:

13 May 2021