Sage Therapeutics, Inc.
NEUROACTIVE STEROID FORMULATIONS AND METHODS OF TREATING CNS DISORDERS

Abstract:

Formulations of comprising a neuroactive steroid, e.g., allopregnanolone; and optionally a cyclodextrin, e.g., a .beta.-cyclodextrin, e.g., a sulfo butyl ether .beta.-cyclodextrin, e.g., a .beta.-cyclodextrin, e.g., a sulfo butyl ether .beta.-cyclodextrin, e.g., CAPTISOL.RTM.; and methods of use in treating CNS disorders.