Sage Therapeutics, Inc.
Neuroactive steroids, compositions, and uses thereof

Last updated:

Abstract:

Described herein are neuroactive steroids of the Formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof; wherein R.sup.1, R.sup.2, R.sup.a, G, X, Y, Z, and n are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. Also provided are pharmaceutical compositions comprising a compound described herein and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

Status:
Grant
Type:

Utility

Filling date:

30 Apr 2019

Issue date:

21 Sep 2021