Sage Therapeutics, Inc.
NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF

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Abstract:

Described herein are neuro-active steroids of the Formula (I): (I) or a pharmaceutically acceptable salt thereof; wherein R.sup.1, R.sup.2, R.sup.a, G, X, Y, Z, and n are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. Also provided are pharmaceutical compositions comprising a compound described herein and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia. ##STR00001##

Status:
Application
Type:

Utility

Filling date:

8 Jan 2021

Issue date:

11 Nov 2021