Sage Therapeutics, Inc.
COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS

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Abstract:

Described herein are neuroactive steroids of the Formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, wherein , A, R.sup.1, R.sup.2, R.sup.3a, R.sup.4a, R.sup.4b, R.sup.5, R.sup.7a, and R.sup.7b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

Status:
Application
Type:

Utility

Filling date:

15 Mar 2022

Issue date:

14 Jul 2022