Selecta Biosciences, Inc.
Tolerogenic synthetic nanocarriers for generating CD8+ regulatory T cells
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Abstract:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.
Status:
Grant
Type:
Utility
Filling date:
27 Jul 2015
Issue date:
15 Oct 2019