Sanofi
Live-Attenuated Yellow Fever Virus Strain Adapted to Grow on Vero Cells and Vaccine Composition Comprising the Same

Abstract:

The invention relates to a live-attenuated yellow fever virus strain adapted to grow on Vero cells from a parent yellow fever virus 17D substrain that is not adapted to grow on Vero cells, wherein said live-attenuated yellow fever virus strain is less neurovirulent than said parent yellow fever virus 17D substrain.