Sanofi
Stopper

Abstract:

A stopper for use in a cartridge or syringe of a medical device .sub.[SL6]is configured to be disposed within a container closure system. The stopper comprises a shell comprising a closed end and an open end with sidewalls extending between the closed end and the open end along a longitudinal axis of the shell. The open end defines a cavity and the sidewalls define an exterior surface sized and shaped to fit inside the container closure system. An insert is configured to be inserted into the cavity, receive a force from a plunger rod, and distribute the force to the shell in order to advance the shell into the container closure system. The closed end of the shell in the cavity defining a convex surface configured to be contacted and deflected by the insert upon insertion into the cavity includes an elastic and/or plastic deformable material.