Sanofi
MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE

Abstract:

The present invention relates to a biologically active single chain Relaxin peptide having the following formula (I) (SEQ ID NO 105): TABLE-US-00001 N.sub.ter-AC-X.sub.10-E-G-R-E-X.sub.15-V-R-X.sub.18-X.sub.19-I-X.sub.21-X.- sub.22-E-G-X.sub.25-S- X.sub.27-X.sub.28-X.sub.29-X.sub.30-X.sub.31-X.sub.32-X.sub.33-NH.sub.2-C.- sub.ter or a salt or solvate thereof. It also concerns a pharmaceutical composition comprising at least one peptide of the invention, and the peptide or the pharmaceutical composition for its use as a medicament.