Sony Group Corporation
TUMOR DETECTION AND SEGMENTATION FOR DPI AI PLATFORM ROUTES

Abstract:

A method of tumor detection and segmentation accepts a first Whole Slide Image (WSI) having a first resolution; creates a corresponding second WSI having a second resolution lower than the first resolution; applies an adaptive thresholding technique to the second WSI to create a background removal mask background; applies the mask to the first WSI to provide a third WSI with extracted patches, characterized by a third resolution, greater than the second resolution and lower than the first resolution; uses a first machine learning system on the third WSI to create a heat map at the third resolution, indicating a subset of the patches likely to include one or more clusters of tumor cells; and uses a second machine learning system on the first WSI and the heat map to segment each patch in a corresponding output image at the first resolution, outlining one or more corresponding clusters.