Spectrum Pharmaceuticals, Inc.
INHIBITORS OF MUTANT FAMILY TYROSINE-KINASES

Abstract:

An epidermal growth factor receptor (EGFR) family tyrosine kinase inhibitor comprising a functional group that can bind to the serine S797 residue in EGFR having a C797S mutation or the serine S805 residue in HER2 having a C805S mutation.