SQZ Biotechnologies Company
INTRACELLULAR DELIVERY OF BIOMOLECULES MEDIATED BY A SURFACE WITH PORES

Abstract:

The present disclosure pertains to methods and devices for delivering a compound into a cell, including passing a cell suspension through a surface containing pores, wherein the pores deform the cell thereby causing a perturbation of the cell such that the compound enters the cell, wherein the cell suspension is contacted with the compound.