Syros Pharmaceuticals, Inc.
Methods of stratifying patients for treatment with retinoic acid receptor-alpha agonists

Abstract:

The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.