Takeda Pharmaceutical Company Limited
COCRYSTAL

Abstract:

Improving the solubility of an organic compound. A cocrystal of (1) 6-ethyl-N-[1-(hydroxyacetyl)piperidin-4-yl]-1-methyl-4-oxo-5-(2-oxo-2-phe- nylethyl)-3-(2,2,2-trifluoroethoxy)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-- 2-carboxamide and (2) L-malic acid or L-tartaric acid.