Telesis Bio, Inc.
IMPROVED PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES

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Abstract:

The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process for enhanced encapsulation of messenger RNA (mRNA) in lipid nanoparticles comprising a step of heating the mRNA-encapsulated lipid nanoparticles in a drug product formulation solution.

Status:
Application
Type:

Utility

Filling date:

14 May 2020

Issue date:

14 Jul 2022