Bio-Techne Corporation
Wnt/sFRP complexes, Wnt-containing compositions, Wnt-expressing cells, and methods of making, purifying, and using same

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Abstract:

This disclosure describes isolated protein complexes including a Wnt and a sFRP; compositions including a Wnt; a cell overexpressing a Wnt and a sFRP; compositions including a cell overexpressing a Wnt and a cell overexpressing a sFRP; methods of making the protein complexes, compositions, and cells; and methods of using the isolated protein complexes, compositions, and cells. This disclosure further describes methods of forming a complex including a Wnt and a sFRP and methods for isolating a Wnt. Also described herein are methods that may be used to purify a Wnt without the use of a detergent.

Status:
Grant
Type:

Utility

Filling date:

9 Oct 2018

Issue date:

29 Jun 2021