Tiziana Life Sciences PLC
Dactinomycin compositions and methods for the treatment of myelodysplastic syndrome and acute myeloid leukemia

Abstract:

The disclosure provides compositions comprising dactinomycin, formulated for delivery by nanoparticle, and methods for treating a myelodysplastic syndrome (MDS) or cancer, for example, NPM1-mutated acute myeloid leukemia (AML), by administration of the compositions of the disclosure.