Trevena, Inc.
Beta-Arrestin Effectors and Compositions and Methods of Use Thereof

Abstract:

This application describes a family of compounds acting as .beta.-arrestin effectors that can be used, for example, for treating acute respiratory distress syndrome, for preventing and treating thrombosis, platelet adhesion, and platelet aggregation, and/or for reducing a D-Dimer response, in a subject with ARDS or a viral infection, such as a coronavirus infection.