Twist Bioscience Corporation
COMPOSITIONS AND METHODS FOR NUCLEIC ACID AMPLIFICATION

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Abstract:

The present disclosure provides compositions, methods and systems for the efficient removal of a non-target nucleic acid sequence from a double stranded nucleic acid amplification product. A non-target nucleic acid sequence may be a primer sequence incorporated into the double stranded nucleic acid molecule during a nucleic acid synthesis or amplification reaction. The non-target nucleic acid sequence may include a nucleobases that are not canonical DNA nucleobases, such as uracil, that can be selectively removed as part of the non-target sequence removal process.

Status:
Application
Type:

Utility

Filling date:

8 Jul 2021

Issue date:

28 Oct 2021