10x Genomics, Inc.
METHODS FOR ANALYZING TARGET NUCLEIC ACIDS AND RELATED COMPOSITIONS

Abstract:

The present disclosure, among other things, provides methods for analyzing a target nucleic acid in a biological sample. In some aspects, the methods involve the use of a set of probe polynucleotides, for example comprising three polynucleotides, for assessing target nucleic acids. In some aspects, the presence, amount and/or sequence of the target nucleic acid is analyzed in situ. In some aspects, the methods involve anchoring or linking a portion of the set of polynucleotides to a scaffold or other nucleic acids. Also provided are polynucleotides, set of polynucleotides, compositions, kits, devices and systems for use in accordance with the methods.