10x Genomics, Inc.
Systems and methods for nucleic acid processing using degenerate nucleotides

Abstract:

Provided herein are compositions, systems and methods for tagging molecular events, reactions, species, etc., but without the need for complex, highly diverse libraries of tagging molecules. Provided are tagging moieties that can have a smaller number, a few, or even a single original "tagging" structure that may be transformed or transformable, in situ, into a collection of larger numbers of unique tagging or "barcode" moieties.