Vascular Biogenics Ltd.
METHODS OF INDUCING RESPONSIVENESS TO ANTI-ANGIOGENIC AGENT

Abstract:

The invention provides methods of inducing or improving responsiveness to a VEGF antagonist to a subject or a subject population comprising administering an adenovirus comprising a nucleic acid construct comprising a F AS-chimera gene operably linked to an endothelial cell-specific promoter and administering the VEGF antagonist.