Vascular Biogenics Ltd.
DIAGNOSTIC METHODS FOR ANTI-ANGIOGENIC AGENT THERAPY

Abstract:

The disclosure provides methods of treating a tumor in a subject who is capable of exhibiting a change in at least one plasma biomarker or cell surface biomarker after administration of at least one priming dose of a vector which comprises a Fas-chimera gene operably linked to an endothelial cell-specific promoter. Also provided are methods of identifying a responder to a Fas-chimera gene therapy in a subject having a tumor.