Wave Life Sciences Ltd.
CHIRAL DESIGN
Last updated:
Abstract:
The present invention relates to chirally controlled oligonucleotides of select designs, chirally controlled oligonucleotide compositions, and methods of making and using the same. In some embodiments, a provided chirally controlled oligonucleotide composition provides different cleavage patterns of a nucleic acid polymer than a reference oligonucleotide composition. In some embodiments, a provided chirally controlled oligonucleotide composition provides single site cleavage within a complementary sequence of a nucleic acid polymer.
Status:
Application
Type:
Utility
Filling date:
9 Sep 2020
Issue date:
22 Apr 2021