Xenon Pharmaceuticals Inc.
Therapeutic compounds and methods of use thereof

Abstract:

The invention provides a compound of formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein the variables X, Y.sup.1--Y.sup.5, R.sup.1, R.sup.2, R.sup.3, R.sup.4, and Het have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.