Xeris Biopharma Holdings, Inc.
Methods for producing stable therapeutic formulations in aprotic polar solvents

Abstract:

Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.