Xeris Biopharma Holdings, Inc.
PRECIPITATION RESISTANT SMALL MOLECULE DRUG FORMULATIONS
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Abstract:
Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
Status:
Application
Type:
Utility
Filling date:
13 May 2021
Issue date:
31 Mar 2022