Xencor, Inc.
PD-1 TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15Ra Fc-FUSION PROTEINS AND PD-1 ANTIGEN BINDING DOMAINS AND USES THEREOF

Abstract:

The present invention is directed to novel PD-1-targeted IL-15/R.alpha.-Fc fusion proteins comprising an IL-15/IL-15R.alpha. Fc-fusion protein and a PD-1 antigen binding domain. The PD-1-targeted IL-15/R.alpha.-Fc fusion proteins can be administered to a patient to treat cancer.