Xencor, Inc.
HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFICATIONS
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Abstract:
The invention relates generally to compositions and methods for purifying the desired species from a mixture of desired heterodimer and contaminating homodimer immunoglobulin variants by modifying the isoelectric point(s) of the individual chains.
Status:
Application
Type:
Utility
Filling date:
12 Oct 2020
Issue date:
16 Sep 2021