Zymergen Inc.
ENGINEERED BIOSYNTHETIC PATHWAYS FOR PRODUCTION OF 3-AMINO-4-HYDROXYBENZOIC ACID BY FERMENTATION

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Abstract:

The present disclosure describes the engineering of microbial cells for fermentative production of 3-amino-4-hydroxybenzoic acid and provides novel engineered microbial cells and cultures, as well as related 3-amino-4-hydroxybenzoic acid production methods. Embodiments 1: An engineered microbial cell that produces 3-amino-4-hydroxybenzoic acid, wherein the engineered microbial cell expresses: (a) a non-native 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy) heptanoate synthase; and (b) a non-native 3-amino-4-benzoic acid synthase.

Status:
Application
Type:

Utility

Filling date:

10 Aug 2020

Issue date:

8 Sep 2022