Zynerba Pharmaceuticals, Inc.
Use of cannabidiol prodrugs in pharmaceutical compositions

Abstract:

Described herein are .Iadd.cannabidiol prodrugs used in pharmaceutical compositions as well as .Iaddend.microneedle drug delivery systems comprising a pharmaceutical compositions comprising pharmaceutically active agents (e.g., cannabidiol and prodrugs of cannabidiol) and microneedle arrays suitable for local and systemic delivery of the active agent to a mammal. Also described herein are methods of using a microneedle transdermal or topical drug delivery systems comprising pharmaceutical compositions, comprising cannabidiol and prodrugs of cannabidiol, and microneedle arrays in the treatment disease, including pancreatitis and pancreatic cancer.