| Utility: Treatment of congenital adrenal hyperplasia Filling date: 6 Sep 2025 Issue date: 26 Apr 2022 | 4 Aug 2021 | 26 Apr 2022 |
| Utility: High dosage valbenazine formulation and compositions, methods, and kits related thereto Filling date: 6 Sep 2025 Issue date: 26 Apr 2022 | 19 Oct 2020 | 26 Apr 2022 |
| Utility: Methods for the Administration of Certain VMAT2 Inhibitors Filling date: 6 Sep 2025 Issue date: 10 Feb 2022 | 21 Oct 2021 | 10 Feb 2022 |
| Utility: CRF1 RECEPTOR ANTAGONIST, PHARMACEUTICAL FORMULATIONS AND SOLID FORMS THEREOF FOR THE TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA Filling date: 6 Sep 2025 Issue date: 27 Jan 2022 | 6 Dec 2019 | 27 Jan 2022 |
| Utility: TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA Filling date: 6 Sep 2025 Issue date: 25 Nov 2021 | 4 Aug 2021 | 25 Nov 2021 |
| Utility: N-[2-(1 -BENZYLPIPERIDIN-4-YL)ETHYL]-4-(PYRAZIN-2-YL)-PIPERAZINE-1 -CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MUSCARINIC RECEPTOR 4 (M4) ANTAGONISTS FOR TREATING NEUROLOGICAL DISEASES Filling date: 6 Sep 2025 Issue date: 4 Nov 2021 | 26 Apr 2021 | 4 Nov 2021 |
| Utility: METHODS FOR THE ADMINISTRATION OF COMT INHIBITORS Filling date: 6 Sep 2025 Issue date: 4 Nov 2021 | 4 Oct 2019 | 4 Nov 2021 |
| Utility: GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO Filling date: 6 Sep 2025 Issue date: 16 Sep 2021 | 18 Dec 2020 | 16 Sep 2021 |
| Utility: METHODS FOR THE ADMINISTRATION OF COMT INHIBITORS Filling date: 6 Sep 2025 Issue date: 22 Jul 2021 | 1 Apr 2021 | 22 Jul 2021 |
| Utility: [9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11BH-pyrido-[2,1-a]is- oquinolin-2-yl]methanol and compounds, compositions and methods relating thereto Filling date: 6 Sep 2025 Issue date: 6 Jul 2021 | 22 Jan 2020 | 6 Jul 2021 |
| Utility: TREATMENT OF HYPERKINETIC MOVEMENT DISORDERS Filling date: 6 Sep 2025 Issue date: 1 Jul 2021 | 15 Sep 2020 | 1 Jul 2021 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 22 Jun 2021 | 8 May 2020 | 22 Jun 2021 |
| Utility: VMAT2 inhibitor compounds and compositions thereof Filling date: 6 Sep 2025 Issue date: 22 Jun 2021 | 17 Apr 2018 | 22 Jun 2021 |
| Utility: Compounds of formulas (VII), (VIII), (IX), (XI), (XII), (XIII), and (XIV) as muscarinic receptor 4(M4) antagonists for treating neurological diseases Filling date: 6 Sep 2025 Issue date: 15 Jun 2021 | 4 Nov 2016 | 15 Jun 2021 |
| Utility: Methods for the Administration of Certain VMAT2 Inhibitors Filling date: 6 Sep 2025 Issue date: 10 Jun 2021 | 17 Dec 2020 | 10 Jun 2021 |
| Utility: High dosage valbenazine formulation and compositions, methods, and kits related thereto Filling date: 6 Sep 2025 Issue date: 8 Jun 2021 | 19 Oct 2020 | 8 Jun 2021 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 8 Jun 2021 | 3 Aug 2020 | 8 Jun 2021 |
| Utility: Substituted triazoles and methods relating thereto Filling date: 6 Sep 2025 Issue date: 1 Jun 2021 | 4 Jun 2020 | 1 Jun 2021 |
| Utility: TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA Filling date: 6 Sep 2025 Issue date: 13 May 2021 | 20 Oct 2020 | 13 May 2021 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 4 May 2021 | 8 May 2020 | 4 May 2021 |
| Utility: Use of Valbenazine for Treating Schizophrenia or Schizoaffective Disorder Filling date: 6 Sep 2025 Issue date: 22 Apr 2021 | 3 Jun 2020 | 22 Apr 2021 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 23 Mar 2021 | 8 May 2020 | 23 Mar 2021 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 9 Mar 2021 | 10 Aug 2020 | 9 Mar 2021 |
| Utility: Gonadotropin-releasing hormone receptor antagonists and methods relating thereto Filling date: 6 Sep 2025 Issue date: 9 Mar 2021 | 2 Jul 2019 | 9 Mar 2021 |
| Utility: METHODS FOR THE ADMINISTRATION OF CERTAIN VMAT2 INHIBITORS Filling date: 6 Sep 2025 Issue date: 25 Feb 2021 | 10 Aug 2020 | 25 Feb 2021 |
| Utility: Methods for the Administration of Certain VMAT2 Inhibitors Filling date: 6 Sep 2025 Issue date: 18 Feb 2021 | 26 Oct 2020 | 18 Feb 2021 |
| Utility: Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyr- ido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) Filling date: 6 Sep 2025 Issue date: 16 Feb 2021 | 15 Jul 2020 | 16 Feb 2021 |
| Utility: Methods for the Administration of Certain VMAT2 Inhibitors Filling date: 6 Sep 2025 Issue date: 11 Feb 2021 | 20 Oct 2020 | 11 Feb 2021 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 9 Feb 2021 | 17 Oct 2020 | 9 Feb 2021 |
| Utility: High Dosage Valbenazine Formulation and Compositions, Methods, and Kits Related Thereto Filling date: 6 Sep 2025 Issue date: 4 Feb 2021 | 19 Oct 2020 | 4 Feb 2021 |
| Utility: High Dosage Valbenazine Formulation and Compositions, Methods, and Kits Related Thereto Filling date: 6 Sep 2025 Issue date: 4 Feb 2021 | 19 Oct 2020 | 4 Feb 2021 |
| Utility: Methods for the Administration of Certain VMAT2 Inhibitors Filling date: 6 Sep 2025 Issue date: 4 Feb 2021 | 17 Oct 2020 | 4 Feb 2021 |
| Utility: Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyr- ido[2,1,-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) Filling date: 6 Sep 2025 Issue date: 2 Feb 2021 | 15 Jul 2020 | 2 Feb 2021 |
| Utility: Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyr- ido[2,1,-a]isoquinolin-2-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) Filling date: 6 Sep 2025 Issue date: 2 Feb 2021 | 15 Jul 2020 | 2 Feb 2021 |
| Utility: Treatment of congenital adrenal hyperplasia Filling date: 6 Sep 2025 Issue date: 2 Feb 2021 | 20 Dec 2018 | 2 Feb 2021 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 29 Dec 2020 | 10 Oct 2017 | 29 Dec 2020 |
| Utility: Methods for the Administration of Certain VMAT2 Inhibitors Filling date: 6 Sep 2025 Issue date: 24 Dec 2020 | 31 Aug 2020 | 24 Dec 2020 |
| Utility: SUBSTITUTED TRIAZOLES AND METHODS RELATING THERETO Filling date: 6 Sep 2025 Issue date: 24 Dec 2020 | 4 Jun 2020 | 24 Dec 2020 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 8 Dec 2020 | 11 May 2020 | 8 Dec 2020 |
| Utility: Methods for the administration of certain VMAT2 inhibitors Filling date: 6 Sep 2025 Issue date: 8 Dec 2020 | 8 May 2020 | 8 Dec 2020 |
| Utility: Valbenazine salts and polymorphs thereof Filling date: 6 Sep 2025 Issue date: 1 Dec 2020 | 12 Jun 2020 | 1 Dec 2020 |
| Utility: Valbenazine salts and polymorphs thereof Filling date: 6 Sep 2025 Issue date: 1 Dec 2020 | 12 Jun 2020 | 1 Dec 2020 |
| Utility: Valbenazine salts and polymorphs thereof Filling date: 6 Sep 2025 Issue date: 24 Nov 2020 | 12 Jun 2020 | 24 Nov 2020 |
| Utility: METHODS FOR THE ADMINISTRATION OF CERTAIN VMAT2 INHIBITORS Filling date: 6 Sep 2025 Issue date: 19 Nov 2020 | 3 Aug 2020 | 19 Nov 2020 |
| Utility: SYNTHETIC METHODS FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYR- IDO[2,1,-A]lSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE) Filling date: 6 Sep 2025 Issue date: 5 Nov 2020 | 15 Jul 2020 | 5 Nov 2020 |
| Utility: SYNTHETIC METHODS FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYR- IDO[2,1,-A]lSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE) Filling date: 6 Sep 2025 Issue date: 5 Nov 2020 | 15 Jul 2020 | 5 Nov 2020 |
| Utility: SYNTHETIC METHODS FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYR- IDO[2,1,-A]lSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE) Filling date: 6 Sep 2025 Issue date: 5 Nov 2020 | 15 Jul 2020 | 5 Nov 2020 |
| Utility: SYNTHETIC METHODS FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYR- IDO[2,1,-A]lSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE) Filling date: 6 Sep 2025 Issue date: 5 Nov 2020 | 15 Jul 2020 | 5 Nov 2020 |
| Utility: VALBENAZINE SALTS AND POLYMORPHS THEREOF Filling date: 6 Sep 2025 Issue date: 29 Oct 2020 | 12 Jun 2020 | 29 Oct 2020 |
| Utility: VALBENAZINE SALTS AND POLYMORPHS THEREOF Filling date: 6 Sep 2025 Issue date: 29 Oct 2020 | 12 Jun 2020 | 29 Oct 2020 |
