Vertex Pharmaceuticals Incorporated
Co-crystals and pharmaceutical compositions comprising the same

Abstract:

The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure: ##STR00001## wherein each of R.sup.1 and R.sup.2 is H or .sup.2H and a co-crystal former selected from adipic acid, citric acid, fumaric acid, maleic acid, succinic acid, or benzoic acid. Also within the scope of this invention are methods of making and using the same.