AbbVie Inc.
PROLINE AMIDE COMPOUNDS AND THEIR AZETIDINE ANALOGUES CARRYING A SPECIFICALLY SUBSTITUTED BENZYL RADICAL

Abstract:

The present invention relates to proline amide compounds and their azetidine derivatives of formula I wherein the variables are as defined in the claims and the description. The invention further relates to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT.sub.2C receptor, their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT.sub.2C receptor, to a method for preventing or treating conditions and disorders which respond to the modulation of the 5-HT.sub.2C receptor, and processes for preparing such compounds and compositions. ##STR00001##