AbbVie Inc.
Inhibitors of tyrosine kinase 2 mediated signaling

Abstract:

Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R.sub.1, R2, R.sub.3, R.sub.4a, R.sub.4b, X.sup.1, X.sup.2, X.sup.3, X.sup.4, X.sup.5, nad n are as defined herein, pharmaeceutical compositions 2C X.sup.5, and n are as defined herein, pharmaceutical compositions comprising same, and methods of preparation and use. ##STR00001##