Sale
HOPKINS JANET JILL officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 11,822 $9.36 $110,666 Sale
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 9,200 $10.74 $98,790 Sale
ELAZZOUZI AMY officer: Vice President, Finance officer: Vice President, Finance
Common Stock 553 $10.74 $5,939 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 5,000 $5.48 $27,400 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 2,631 $4.25 $11,182 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 17,500 $2.74 $47,950 Sale
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 25,131 $12.03 $302,351 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 5,000 $5.48 $27,400 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 17,500 $2.74 $47,950 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 2,631 $4.25 $11,182 Option
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 24,992 $2.74 $68,478 Option
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Stock Option (Right to Buy) 24,992 $2.74 $68,478 Sale
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 24,992 $12.04 $300,829 Sale
PLAVSIC MARK officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 7,383 $9.85 $72,723 Option
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 5,474 $5.76 $31,530 Option
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Stock Option (Right to Buy) 5,474 $5.76 $31,530 Sale
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 15,853 $7.64 $121,149 Sale
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 6,609 $7.64 $50,519 Purchase
MATRIX CAPITAL MANAGEMENT COMPANY, LP 10 percent owner 10 percent owner
Common Stock, par value $0.00001 per share (Common Stock) 1,560,000 $9 $14,040,000 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 9,601 $7.3 $70,087 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 10,000 $7.3 $73,000 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 76,000 $7.17 $544,920 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 47,000 $7.17 $336,990 Option
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Stock Option (Right to Buy) 3,800 $2.74 $10,412 Option
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 3,800 $2.74 $10,412 Sale
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 7,449 $12.03 $89,611 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 3,900 $2.74 $10,686 Option
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 3,900 $2.74 $10,686 Sale
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 3,900 $12.07 $47,054 Sale
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 3,385 $6.82 $23,092 Sale
DE LOS PINOS ELISABET director, officer: See Remarks director, officer: See Remarks
Common Stock 9,586 $6.83 $65,482 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 6,566 $8.61 $56,514 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 13,500 $8.27 $111,659 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 904 $10.51 $9,501 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 96 $10 $960 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 300 $10 $3,000 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 2,000 $9.75 $19,500 Purchase
MATRIX CAPITAL MANAGEMENT COMPANY, LP 10 percent owner 10 percent owner
Common Stock, par value $0.00001 per share ("Common Stock") 1,250,000 $12 $15,000,000 Sale
FEDER JULIE B officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 2,015 $12.45 $25,089 Sale
DE ROSCH MARK officer: Chief Operating Officer officer: Chief Operating Officer
Common Stock 1,115 $12.46 $13,890 Sale
DE LOS PINOS ELISABET director, officer: President and Chi.. director, officer: President an..
Common Stock 5,706 $12.46 $71,080 Sale
RICH CADMUS officer: Chief Medical Officer, Head of R&D officer: Chief Medical Officer,..
Common Stock 1,672 $12.45 $20,813 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 20,000 $13.99 $279,800 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 7,000 $13.99 $97,930 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 10,000 $15.04 $150,400 Purchase
JOHNSON DAVID MICHAEL director director
Common Stock 3,000 $15.04 $45,120 Purchase
MEDICXI VENTURES MANAGEMENT (JERSEY) LTD 10 percent owner 10 percent owner
Common Stock 16,475 $14 $230,650 Purchase
MEDICXI VENTURES MANAGEMENT (JERSEY) LTD 10 percent owner 10 percent owner
Common Stock 693,525 $14 $9,709,350 Purchase
MATRIX CAPITAL MANAGEMENT COMPANY, LP 10 percent owner 10 percent owner
Common Stock 1,785,000 $14 $24,990,000