Sale 
    GARRISON MICHAEL DAVID  officer: EVP & President, Medical  officer: EVP & President, Medical 
  Common Stock   2,838  $223.33    $633,811     Sale 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Common Stock   638  $219.03    $139,741     Option 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Common Stock   6,339  $167.91    $1,064,381     Sale 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Common Stock   4,483  $221.01    $990,788     Option 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Common Stock   6,995  $147.68    $1,033,022     Option 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Stock Appreciation Rights   13,334  $157.8    $2,104,039     Sale 
    NEAL SHANA CAROL  officer: EVP and Chief People Officer  officer: EVP and Chief People O.. 
  Common Stock   1,000  $220.49    $220,490     Sale 
    SHAN DAVID  officer: EVP and Chief ISC Officer  officer: EVP and Chief ISC Offi.. 
  Common Stock   1,500  $220.25    $330,375     Option 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Common Stock   5,295  $132.54    $701,799     Option 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Stock Appreciated Rights   5,295  $132.54    $701,799     Sale 
    SPOEREL THOMAS J  officer: SVP,Controller&Chief Acct Off  officer: SVP,Controller&Chief A.. 
  Common Stock   300  $239.31    $71,793     Sale 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Common Stock   800  $235.29    $188,232     Sale 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Common Stock   1,400  $236.99    $331,786     Sale 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Common Stock   1,100  $237.46    $261,206     Sale 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Common Stock   1,700  $236.28    $401,676     Sale 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Common Stock   1,572  $237.14    $372,784     Sale 
    GOETTE ROLAND  officer: EVP and President EMEA  officer: EVP and President EMEA 
  Common Stock   28  $237.9    $6,661     Sale 
    GARRISON MICHAEL DAVID  officer: EVP & President Medical  officer: EVP & President Medical 
  Common Stock   1,715  $232.81    $399,269     Sale 
    SPOEREL THOMAS J  officer: SVP,Controller&Chief Acct Off  officer: SVP,Controller&Chief A.. 
  Common Stock   282  $238.29    $67,198     Sale 
    GARRISON MICHAEL DAVID  officer: EVP & President Medical  officer: EVP & President Medical 
  Common Stock   1,239  $232.46    $288,018     Sale 
    BYRD RICHARD  officer: EVP & President Interventional  officer: EVP & President Interv.. 
  Common Stock   2,156  $238.47    $514,141     Option 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Common Stock   3,544  $107.12    $379,633     Option 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Stock Appreciation Rights   3,544  $107.12    $379,633     Sale 
    BYRD RICHARD  officer: EVP & President Interventional  officer: EVP & President Interv.. 
  Common Stock   459  $274.48    $125,986     Sale 
    FRASER CLAIRE  director  director 
  Common Stock   848  $281.66    $238,848     Option 
    HICKEY DAVID  officer: EVP & President, Life Sciences  officer: EVP & President, Life .. 
  Common Stock   3,883  $132.54    $514,653     Sale 
    HICKEY DAVID  officer: EVP & President, Life Sciences  officer: EVP & President, Life .. 
  Common Stock   2,974  $277.85    $826,326     Option 
    HICKEY DAVID  officer: EVP & President, Life Sciences  officer: EVP & President, Life .. 
  Stock Appreciation Rights   3,883  $132.54    $514,653     Sale 
    GARRISON MICHAEL DAVID  officer: EVP & President Medical  officer: EVP & President Medical 
  Common Stock   1,300  $277.13    $360,269     Sale 
    BYRD RICHARD  officer: EVP & President Interventional  officer: EVP & President Interv.. 
  Common Stock   1,421  $248.6    $353,261     Option 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Common Stock   4,617  $74.94    $345,998     Option 
    GOETTE ROLAND  officer: EVP and President, EMEA  officer: EVP and President, EMEA 
  Stock Appreciation Rights   4,617  N/A   N/A      Sale 
    HICKEY DAVID  officer: EVP & President, Life Sciences  officer: EVP & President, Life .. 
  Common Stock   475  $265    $125,875     Option 
    POLEN THOMAS E JR  officer: Chairman, CEO and President  officer: Chairman, CEO and Pres.. 
  Common Stock   15,000  $167.91    $2,518,650     Sale 
    POLEN THOMAS E JR  officer: Chairman, CEO and President  officer: Chairman, CEO and Pres.. 
  Common Stock   9,500  $265.13    $2,518,735     Sale 
    KHICHI SAMRAT S.  officer: EVP and General Counsel  officer: EVP and General Counsel 
  Common Stock   7,295  $260.44    $1,899,910     Option 
    KHICHI SAMRAT S.  officer: EVP and General Counsel  officer: EVP and General Counsel 
  Stock Appreciation Rights   12,489  N/A   N/A      Sale 
    POLEN THOMAS E JR  officer: Executive Vice President  officer: Executive Vice President 
  Common Stock   1,652  $260    $429,520     Option 
    POLEN THOMAS E JR  officer: Executive Vice President  officer: Executive Vice President 
  Common Stock   3,825  $147.68    $564,876     Sale 
    SPOEREL THOMAS J  officer: VP Controller & Chief Acct Off  officer: VP Controller & Chief .. 
  Common Stock   443  $260    $115,180     Option 
    SPOEREL THOMAS J  officer: VP Controller & Chief Acct Off  officer: VP Controller & Chief .. 
  Stock Appreciation Rights   1,026  N/A   N/A      Sale 
    HICKEY DAVID  officer: EVP & President, Life Sciences  officer: EVP & President, Life .. 
  Common Stock   475  $256    $121,600     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Stock Appreciation Rights   3,684  $227.47    $837,999     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Stock Appreciation Rights   1,244  $227.47    $282,973     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Stock Appreciation Rights   4,630  $255.22    $1,181,669     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Stock Appreciation Rights   6,789  $242.1    $1,643,617     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Stock Appreciation Rights   10,245  $217.84    $2,231,771     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Common Stock   3,684  $227.47    $837,999     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Common Stock   1,244  $227.47    $282,973     Option 
    LARSON BETTY D  officer: EVP HR & CHRO  officer: EVP HR & CHRO 
  Common Stock   4,630  $255.22    $1,181,669