Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 65,500 $4.98 $326,321 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 20,356 $4.69 $95,409 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 74,684 $4.97 $370,955 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 110,210 $4.97 $547,413 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 5,500 $4.9 $26,945 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 70,560 $4.92 $347,226 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 124,582 $4.97 $618,550 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 141,083 $5.04 $711,058 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 82,835 $5.26 $435,546 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 1,206,519 $5.33 $6,428,333 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 109,425 $5.49 $601,181 Purchase
FECZKO JOSEPH M director director
Common Stock 10,000 $6.03 $60,260 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 9,677 $6.09 $58,923 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 315,958 $5.94 $1,877,106 Sale
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 1,783 $4.3 $7,667 Option
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 5,459 $8.6 $46,958 Option
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Employee Stock Option (right to buy) 5,459 $8.6 $46,958 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 5,000 $6 $30,000 Sale
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 5,000 $6 $30,000 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 5,000 $6 $30,000 Sale
LUCAS ROGER C director director
Common Stock 5,000 $13.42 $67,085 Sale
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 6,250 $13.82 $86,381 Option
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 5,459 $9.41 $51,364 Sale
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 5,000 $6 $30,000 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 10,000 $6 $60,000 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 8,334 $6 $50,004 Option
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Employee Stock Option (right to buy) 5,459 $9.41 $51,364 Sale
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 1,783 $4.3 $7,667 Sale
SCHALL THOMAS J. director, officer: President and CEO director, officer: President an..
Common Stock 2,585 $14.54 $37,596 Sale
SCHALL THOMAS J. director, officer: President and CEO director, officer: President an..
Common Stock 19,504 $14.38 $280,370 Sale
LUCAS ROGER C director director
Common Stock 5,000 $13.43 $67,155 Sale
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 6,250 $13.88 $86,756 Sale
SCHALL THOMAS J. director, officer: President and CEO director, officer: President an..
Common Stock 311 $14.5 $4,510 Option
KANAYA SUSAN M officer: EVP, CFO and Sec. officer: EVP, CFO and Sec.
Employee Stock Option (right to buy) 36,942 $2 $73,884 Sale
KANAYA SUSAN M officer: EVP, CFO and Sec. officer: EVP, CFO and Sec.
Common Stock 36,942 $2 $73,884 Option
KANAYA SUSAN M officer: EVP, CFO and Sec. officer: EVP, CFO and Sec.
Common Stock 36,942 $2 $73,884 Sale
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 3,016 $14 $42,224 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 3,016 $14 $42,224 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 3,016 $14 $42,224 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 117 $14 $1,638 Sale
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 117 $14 $1,638 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 117 $14 $1,638 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 1,867 $6 $11,202 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 1,867 $6 $11,202 Sale
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 1,867 $6 $11,202 Sale
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 6,250 $13 $81,250 Option
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 1,783 $4.3 $7,667 Option
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Employee Stock Option (right to buy) 1,783 $4.3 $7,667 Sale
CAPPEL MARKUS J. officer: Chief Bus. Officer & Treasurer officer: Chief Bus. Officer & T..
Common Stock 1,783 $4.3 $7,667 Option
BEKKER PETRUS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 5,000 $6 $30,000