Purchase
WEISSMAN JAMES B officer: Chief Operating Officer & EVP officer: Chief Operating Office..
Common Stock 5,000 $3.27 $16,365 Option
LANGER DENNIS director director
Employee Stock Option (Right to Buy) 34,722 $3.42 $118,749 Option
LANGER DENNIS director director
Common Stock 34,722 $3.42 $118,749 Sale
SKYLINE VENTURE PARTNERS V LP other: former 10% holder other: former 10% holder
Common Stock 37,532 $26.02 $976,583 Option
FAMBROUGH DOUGLAS director, officer: President and CEO director, officer: President an..
Employee Stock Option (Right to Buy) 1,050 $3.42 $3,591 Option
FAMBROUGH DOUGLAS director, officer: President and CEO director, officer: President an..
Common Stock 2,500 $3.42 $8,550 Sale
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 121,965 $11.5 $1,402,598 Sale
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 100,000 $11.55 $1,154,500 Sale
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 100,000 $11 $1,100,000 Sale
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 214,164 $9.2 $1,970,309 Sale
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 51,449 $10.01 $515,004 Sale
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 36,115 $11.02 $397,987 Sale
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 30,214 $12.07 $364,653 Sale
BROOKSIDE CAPITAL MANAGEMENT LLC 10 percent owner 10 percent owner
Common Stock 264,937 $38.19 $10,116,619 Sale
BROOKSIDE CAPITAL MANAGEMENT LLC 10 percent owner 10 percent owner
Common Stock 9,301 $36.5 $339,487 Sale
BROOKSIDE CAPITAL MANAGEMENT LLC 10 percent owner 10 percent owner
Common Stock 250,400 $35.42 $8,867,916 Sale
BROOKSIDE CAPITAL MANAGEMENT LLC 10 percent owner 10 percent owner
Common Stock 1,500 $37.77 $56,655 Sale
BROOKSIDE CAPITAL MANAGEMENT LLC 10 percent owner 10 percent owner
Common Stock 260,000 $38.19 $9,928,100 Purchase
HOFFMAN STEPHEN J director director
Common Stock 200,000 $15 $3,000,000 Purchase
FLYNN JAMES E 10 percent owner, other: Possible Member of .. 10 percent owner, other: Possib..
Common Stock 1,000,000 $15 $15,000,000 Purchase
SKYLINE VENTURE PARTNERS V LP other: former 10% holder other: former 10% holder
Common Stock 200,000 $15 $3,000,000 Purchase
RA CAPITAL MANAGEMENT, LLC 10 percent owner 10 percent owner
Common Stock, par value $0.0001 per share 1,000,000 $15 $15,000,000 Purchase
MADDEN DAVID director director
Common Stock 7,500 $15 $112,500 Purchase
FAMBROUGH DOUGLAS director, officer: President and CEO director, officer: President an..
Common Stock 5,000 $15 $75,000 Purchase
WEISSMAN JAMES B officer: Chief Operating Officer & EVP officer: Chief Operating Office..
Common Stock 1,000 $15 $15,000 Option
WEISSMAN JAMES B officer: Chief Operating Officer & EVP officer: Chief Operating Office..
Employee Stock Option (right to buy) 11,283 $1.71 $19,294 Option
WEISSMAN JAMES B officer: Chief Operating Officer & EVP officer: Chief Operating Office..
Common Stock 11,283 $3.24 $36,557 Option
LANGER DENNIS director director
Employee Stock Option (right to buy) 8,873 N/A N/A Option
LANGER DENNIS director director
Common Stock 8,873 $3.42 $30,346 Option
MADDEN DAVID director director
Employee Stock Option (right to buy) 1,200 $3.42 $4,104 Option
MADDEN DAVID director director
Common Stock 112,511 $3.42 $384,788 Option
FAMBROUGH DOUGLAS director, officer: President and CEO director, officer: President an..
Employee Stock Option (right to buy) 9,300 $1.71 $15,903 Option
WEISSMAN JAMES B officer: Chief Operating Officer & EVP officer: Chief Operating Office..
Employee Stock Option (right to buy) 833 N/A N/A Option
FAMBROUGH DOUGLAS director, officer: President and CEO director, officer: President an..
Common Stock 9,300 $3.42 $31,806 Option
WEISSMAN JAMES B officer: Chief Operating Officer & EVP officer: Chief Operating Office..
Common Stock 833 $3.42 $2,849