Sale
ZHEN MARIANNE officer: Chief Accounting Officer officer: Chief Accounting Officer
Common Stock 5,589 $14.01 $78,302 Sale
ZHEN MARIANNE officer: Chief Accounting Officer officer: Chief Accounting Officer
Common Stock 5,405 $13.97 $75,508 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 62,000 $13.13 $814,184 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 8,000 $13.05 $104,384 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 7,000 $13.04 $91,294 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 120,000 $13.01 $1,560,600 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 30,000 $13.12 $393,720 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 50,000 $13.09 $654,350 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 36,000 $13.48 $485,136 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 20,000 $13.05 $261,080 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 50,000 $13.07 $653,700 Purchase
DENNER ALEXANDER J 10 percent owner 10 percent owner
Common Stock, par value $0.01 per share 290,000 $12.34 $3,577,440 Purchase
RAIFELD PAVEL officer: Chief Executive Officer officer: Chief Executive Officer
Common Stock 3,000 $10.87 $32,604 Sale
ZHEN MARIANNE officer: Chief Accounting Officer officer: Chief Accounting Officer
Common Stock 1,129 $15.89 $17,940 Sale
ZHEN MARIANNE officer: Chief Accounting Officer officer: Chief Accounting Officer
Common Stock 2,802 $16.02 $44,888 Purchase
BICKERSTAFF GEORGE director director
Common Stock 10,000 $13.46 $134,620 Purchase
BICKERSTAFF GEORGE director director
Common Stock 10,000 $13.46 $134,620 Sale
GLAXOSMITHKLINE PLC 10 percent owner 10 percent owner
Common Stock 32,005,260 $12.25 $392,064,435 Sale
ZHEN MARIANNE officer: Chief Accounting Officer officer: Chief Accounting Officer
Common Stock 2,954 N/A N/A Purchase
BICKERSTAFF GEORGE director director
Common Stock 15,000 N/A N/A Sale
ZHEN MARIANNE officer: Chief Accounting Officer officer: Chief Accounting Officer
Common Stock 5,617 N/A N/A Purchase
BICKERSTAFF GEORGE director director
Common Stock 10,000 N/A N/A Purchase
HULME GEOFFREY officer: Interim Principal Exec Officer officer: Interim Principal Exec..
Common Stock 7,000 N/A N/A Sale
ABERCROMBIE GEORGE B officer: Sr. VP & Chief Comm. Officer officer: Sr. VP & Chief Comm. O..
Common Stock 8,000 N/A N/A Sale
WITEK THEODORE J. JR. officer: Sr. VP & Chief Scientific O.. officer: Sr. VP & Chief Scienti..
Common Stock 8,504 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 5,808 N/A N/A Sale
ABERCROMBIE GEORGE B officer: Sr. VP & Chief Comm. Officer officer: Sr. VP & Chief Comm. O..
Common Stock 8,000 N/A N/A Sale
WITEK THEODORE J. JR. officer: Sr. VP & Chief Scientific O.. officer: Sr. VP & Chief Scienti..
Common Stock 9,890 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 5,378 N/A N/A Sale
ABERCROMBIE GEORGE B officer: Sr. VP & Chief Comm. Officer officer: Sr. VP & Chief Comm. O..
Common Stock 8,000 N/A N/A Sale
AGUIAR MICHAEL W director, officer: President & Chief Exec.. director, officer: President & ..
Common Stock 12,022 N/A N/A Sale
WITEK THEODORE J. JR. officer: Sr. VP & Chief Scientific O.. officer: Sr. VP & Chief Scienti..
Common Stock 13,000 N/A N/A Sale
ABERCROMBIE GEORGE B officer: Sr. VP & Chief Comm. Officer officer: Sr. VP & Chief Comm. O..
Common Stock 5,215 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 13,460 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 1,825 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 1,825 N/A N/A Sale
WITEK THEODORE J. JR. officer: Sr. VP & Chief Scientific O.. officer: Sr. VP & Chief Scienti..
Common Stock 7,815 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 1,825 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 1,825 N/A N/A Sale
WITEK THEODORE L JR
Common Stock 3,700 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 1,800 N/A N/A Sale
DESPARBES ERIC officer: SVP and CFO officer: SVP and CFO
Common Stock 3,700 N/A N/A Sale
TYREE JAMES L director director
Common Stock 813 N/A N/A Purchase
GLAXOSMITHKLINE PLC 10 percent owner 10 percent owner
Common Stock 245,828 N/A N/A Sale
TYREE JAMES L director director
Common Stock 2,438 N/A N/A Option
WALTRIP WILLIAM H director director
Stock Option (Right to Buy) 16,313 N/A N/A Sale
WALTRIP WILLIAM H director director
Common Stock 16,313 N/A N/A Option
WALTRIP WILLIAM H director director
Common Stock 16,313 N/A N/A Purchase
GLAXOSMITHKLINE PLC 10 percent owner 10 percent owner
Common Stock 85,579 N/A N/A Purchase
GLAXOSMITHKLINE PLC 10 percent owner 10 percent owner
Common Stock 92,674 N/A N/A