Loxo Oncology Inc.
Pyrazolopyrimidine derivatives useful as inhibitors of Bruton's tyrosine kinase

Abstract:

This invention relates to compounds of formula (I). The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK). The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of Bruton's tyrosine kinase, for example cancer, lymphoma, leukemia and immunological diseases. ##STR00001##