NGM Biopharmaceuticals, Inc.
Angiopoietin-like protein 8 polypeptide fragments and compositions thereof

Abstract:

Methods and compositions for reducing one or more of triglyceride levels, total cholesterol levels and LDL cholesterol levels in a subject are provided. The methods include administering a fragment of ANGPTL8 to a subject having or at risk of developing elevated triglyceride levels, elevated total cholesterol levels and/or elevated LDL cholesterol levels.