| Utility: METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS Filling date: 8 Sep 2025 Issue date: 18 Aug 2022 | 29 Nov 2021 | 18 Aug 2022 |
| Utility: COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 11 Aug 2022 | 18 Apr 2022 | 11 Aug 2022 |
| Utility: 2,3,5-TRIMETHYL-6-NONYLCYCLOHEXA-2,5-DIENE-1,4-DIONE FOR SUPPRESSING AND TREATING ALPHA-SYNUCLEINOPATHIES, TAUOPATHIES, AND OTHER DISORDERS Filling date: 8 Sep 2025 Issue date: 14 Jul 2022 | 25 Jan 2022 | 14 Jul 2022 |
| Utility: COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 30 Jun 2022 | 12 May 2020 | 30 Jun 2022 |
| Utility: COMPOUND FORM HAVING ENHANCED BIOAVAILABILITY AND FORMULATIONS THEREOF Filling date: 8 Sep 2025 Issue date: 16 Jun 2022 | 9 Mar 2020 | 16 Jun 2022 |
| Utility: DISPERSIBLE TABLET COMPOSITION Filling date: 8 Sep 2025 Issue date: 9 Jun 2022 | 10 Apr 2020 | 9 Jun 2022 |
| Utility: METHOD FOR TREATING NONSENSE MUTATION MEDIATED DUCHENNE MUSCULAR DYSTROPHY IN PEDIATRIC PATIENTS Filling date: 8 Sep 2025 Issue date: 9 Jun 2022 | 9 Apr 2020 | 9 Jun 2022 |
| Utility: NOVEL RNA TRANSCRIPT Filling date: 8 Sep 2025 Issue date: 26 May 2022 | 11 Nov 2021 | 26 May 2022 |
| Utility: TABLET FOR USE IN TREATING HUNTINGTON'S DISEASE AND METHOD OF MAKING THE SAME Filling date: 8 Sep 2025 Issue date: 19 May 2022 | 28 Jan 2022 | 19 May 2022 |
| Utility: COMBINATIONS USEFUL IN A METHOD FOR TREATING SARCOMA Filling date: 8 Sep 2025 Issue date: 19 May 2022 | 27 Mar 2020 | 19 May 2022 |
| Utility: VECTOR AND METHOD FOR TREATING ANGELMAN SYNDROME Filling date: 8 Sep 2025 Issue date: 19 May 2022 | 20 Mar 2020 | 19 May 2022 |
| Utility: METHOD FOR TREATING A MULTIPLE MYELOMA Filling date: 8 Sep 2025 Issue date: 12 May 2022 | 26 Feb 2020 | 12 May 2022 |
| Utility: TREATMENT OF LEIGH SYNDROME AND LEIGH-LIKE SYNDROME WITH TOCOTRIENOL QUINONES Filling date: 8 Sep 2025 Issue date: 5 May 2022 | 11 Aug 2021 | 5 May 2022 |
| Utility: THIOENO[3,2-B] PYRIDIN-7-AMINE COMPOUNDS FOR TREATING FAMILIAL DYSAUTONOMIA Filling date: 8 Sep 2025 Issue date: 5 May 2022 | 10 Feb 2020 | 5 May 2022 |
| Utility: PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS FOR TREATING FAMILIAL DYSAUTONOMIA Filling date: 8 Sep 2025 Issue date: 5 May 2022 | 10 Feb 2020 | 5 May 2022 |
| Utility: 2,3,5-TRIMETHYL-6-NONYLCYCLOHEXA-2,5-DIENE-1,4-DIONE FOR SUPPRESSING AND TREATING ALPHA-SYNUCLEINOPATHIES, TAUOPATHIES, AND OTHER DISORDERS Filling date: 8 Sep 2025 Issue date: 7 Apr 2022 | 10 Nov 2021 | 7 Apr 2022 |
| Utility: REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS Filling date: 8 Sep 2025 Issue date: 24 Feb 2022 | 28 May 2021 | 24 Feb 2022 |
| Utility: METHODS FOR ENRICHING ALPHA-TOCOTRIENOL FROM MIXED TOCOL COMPOSITIONS Filling date: 8 Sep 2025 Issue date: 17 Feb 2022 | 26 Oct 2021 | 17 Feb 2022 |
| Utility: HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 9 Dec 2021 | 25 Jun 2019 | 9 Dec 2021 |
| Utility: METHODS OF ADMINISTERING DEFLAZACORT THERAPY Filling date: 8 Sep 2025 Issue date: 25 Nov 2021 | 4 Aug 2021 | 25 Nov 2021 |
| Utility: CRYSTALLINE FORMS OF 3-[5-(2-FLUOROPHENYL)-[1,2,4]OXADIAZOL-3-YL]-BENZOIC ACID FOR THE TREATMENT OF DISEASE Filling date: 8 Sep 2025 Issue date: 28 Oct 2021 | 24 Feb 2021 | 28 Oct 2021 |
| Utility: TREATMENT OF OXIDATIVE STRESS DISORDERS INCLUDING CONTRAST NEPHROPATHY, RADIATION DAMAGE AND DISRUPTIONS IN THE FUNCTION OF RED CELLS Filling date: 8 Sep 2025 Issue date: 21 Oct 2021 | 29 Mar 2021 | 21 Oct 2021 |
| Utility: HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 16 Sep 2021 | 25 Jun 2019 | 16 Sep 2021 |
| Utility: 2,3,5-TRIMETHYL-6-NONYLCYCLOHEXA-2,5-DIENE-1,4-DIONE FOR SUPPRESSING AND TREATING ALPHA-SYNUCLEINOPATHIES, TAUOPATHIES, AND OTHER DISORDERS Filling date: 8 Sep 2025 Issue date: 9 Sep 2021 | 30 Mar 2021 | 9 Sep 2021 |
| Utility: METHODS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 9 Sep 2021 | 9 Nov 2020 | 9 Sep 2021 |
| Utility: COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY Filling date: 8 Sep 2025 Issue date: 9 Sep 2021 | 5 Oct 2020 | 9 Sep 2021 |
| Utility: FLUOROALKYL, FLUOROALKOXY, PHENOXY, HETEROARYLOXY, ALKOXY, AND AMINE 1,4-BENZOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS Filling date: 8 Sep 2025 Issue date: 5 Aug 2021 | 12 Apr 2021 | 5 Aug 2021 |
| Utility: METHOD FOR TREATING PANCREATIC CANCER Filling date: 8 Sep 2025 Issue date: 5 Aug 2021 | 17 Aug 2019 | 5 Aug 2021 |
| Utility: HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 5 Aug 2021 | 25 Jun 2019 | 5 Aug 2021 |
| Utility: BIOAVAILABLE ORAL DOSAGE FORMS Filling date: 8 Sep 2025 Issue date: 8 Jul 2021 | 2 Aug 2019 | 8 Jul 2021 |
| Utility: 4-(p-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES Filling date: 8 Sep 2025 Issue date: 17 Jun 2021 | 22 Feb 2021 | 17 Jun 2021 |
| Utility: COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY Filling date: 8 Sep 2025 Issue date: 20 May 2021 | 16 Nov 2020 | 20 May 2021 |
| Utility: TREATMENT OF METHYLMALONIC ACIDURIA, ISOVALERIC ACIDURIA, AND OTHER ORGANIC ACIDURIAS WITH TOCOTRIENOL QUINONES Filling date: 8 Sep 2025 Issue date: 20 May 2021 | 17 Sep 2020 | 20 May 2021 |
| Utility: TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS Filling date: 8 Sep 2025 Issue date: 6 May 2021 | 10 Aug 2020 | 6 May 2021 |
| Utility: METHODS FOR MODULATING RNA SPLICING Filling date: 8 Sep 2025 Issue date: 11 Mar 2021 | 13 Apr 2020 | 11 Mar 2021 |
| Utility: 2-SUBSTITUTED AMINO-NAPHTH (1,2-D) IMIDAZOL-5-ONE COMPOUNDS OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF Filling date: 8 Sep 2025 Issue date: 4 Mar 2021 | 10 Aug 2020 | 4 Mar 2021 |
| Utility: METHODS FOR DOSING AN ORALLY ACTIVE 1,2,4-OXADIAZOLE FOR NONSENSE MUTATION SUPPRESSION THERAPY Filling date: 8 Sep 2025 Issue date: 11 Feb 2021 | 23 Oct 2020 | 11 Feb 2021 |
| Utility: COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 28 Jan 2021 | 27 Mar 2019 | 28 Jan 2021 |
| Utility: POLYMORPHIC AND AMORPHOUS FORMS OF (R)-2-HYDROXY-2-METHYL-4-(2,4,5-TRIMETHYL-3,6-DIOXOCYCLOHEXA-1,4-DIENYL)B- UTANAMIDE Filling date: 8 Sep 2025 Issue date: 21 Jan 2021 | 1 Jul 2020 | 21 Jan 2021 |
| Utility: COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE Filling date: 8 Sep 2025 Issue date: 14 Jan 2021 | 26 Mar 2019 | 14 Jan 2021 |
| Utility: METHODS FOR ENRICHING ALPHA-TOCOTRIENOL FROM MIXED TOCOL COMPOSITIONS Filling date: 8 Sep 2025 Issue date: 3 Dec 2020 | 17 Aug 2020 | 3 Dec 2020 |
| Utility: METHODS FOR MODIFYING RNA SPLICING Filling date: 8 Sep 2025 Issue date: 26 Nov 2020 | 13 Jun 2018 | 26 Nov 2020 |
| Utility: TREATMENT OF LEIGH SYNDROME AND LEIGH-LIKE SYNDROME WITH TOCOTRIENOL QUINONES Filling date: 8 Sep 2025 Issue date: 19 Nov 2020 | 4 Aug 2020 | 19 Nov 2020 |
| Utility: CRYSTALLINE FORMS OF 3-[5-(2-FLUOROPHENYL)-[1,2,4]OXADIAZOL-3-YL]-BENZOIC ACID FOR THE TREATMENT OF DISEASE Filling date: 8 Sep 2025 Issue date: 22 Oct 2020 | 7 Jul 2020 | 22 Oct 2020 |
| Utility: FLUOROALKYL, FLUOROALKOXY, PHENOXY, HETEROARYLOXY, ALKOXY, AND AMINE 1,4-BENZOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS Filling date: 8 Sep 2025 Issue date: 22 Oct 2020 | 6 Jul 2020 | 22 Oct 2020 |
| Utility: METHOD OF INHIBITING OR REDUCING A CORONAVIRIDAE VIRUS INFECTION Filling date: 8 Sep 2025 Issue date: 8 Oct 2020 | 23 Jun 2020 | 8 Oct 2020 |
| Utility: COMPOSITIONS FOR AN ORALLY ACTIVE 1,2,4-OXADIAZOLE FOR THE TREATMENT OF DISEASE Filling date: 8 Sep 2025 Issue date: 20 Aug 2020 | 5 May 2020 | 20 Aug 2020 |
| Utility: HYDROGEN ISOTOPE-ENRICHED ANALOGUES OF 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUNDS, COMPOSITIONS AND USES THEREOF Filling date: 8 Sep 2025 Issue date: 20 Aug 2020 | 15 Nov 2016 | 20 Aug 2020 |
| Utility: DHODH INHIBITOR FOR USE IN TREATING HEMATOLOGIC CANCERS Filling date: 8 Sep 2025 Issue date: 13 Aug 2020 | 1 Aug 2018 | 13 Aug 2020 |
| Utility: METHODS FOR TREATING EPILEPSY Filling date: 8 Sep 2025 Issue date: 18 Jun 2020 | 7 Nov 2019 | 18 Jun 2020 |
