Option
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock 15,000 $17.82 $267,345 Sale
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock 15,000 $146.91 $2,203,650 Option
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock Options 15,000 $17.82 $267,345 Option
GESTEN SAMUEL J officer: Chief Legal Officer officer: Chief Legal Officer
Common Stock 29,682 $27.37 $812,248 Sale
GESTEN SAMUEL J officer: Chief Legal Officer officer: Chief Legal Officer
Common Stock 29,682 $134.71 $3,998,462 Option
GESTEN SAMUEL J officer: Chief Legal Officer officer: Chief Legal Officer
Common Stock Options 25,187 $26.55 $668,790 Sale
WILLIAMS PATRICK F. officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 2,500 $140.58 $351,450 Option
SILVERMAN LOU director director
Common Stock 19,921 $77.43 $1,542,383 Sale
SILVERMAN LOU director director
Common Stock 10,000 $9.31 $93,100 Option
SILVERMAN LOU director director
Common Stock Options 10,000 $9.31 $93,100 Option
WILLIAMS PATRICK F. officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 5,121 N/A N/A Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 130,000 $155.19 $20,174,700 Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 30,735 $155.84 $4,789,742 Option
FARRELL STEPHEN C director director
Common Stock 404 N/A N/A Option
FARRELL STEPHEN C director director
Common Stock Options 850 N/A N/A Option
KLIMAN GILBERT H director director
Common Stock Options 850 $154.96 $131,716 Option
SILVERMAN LOU director director
Common Stock 807 N/A N/A Option
YU K PEONY director director
Common Stock Options 850 N/A N/A Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 67,708 $157.83 $10,686,354 Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 13,236 N/A N/A Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 63,896 N/A N/A Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 30,543 N/A N/A Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 35,380 $147.46 $5,217,135 Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 21,895 $147.79 $3,235,862 Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 2,275 $147.05 $334,539 Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 1,014 $146.36 $148,409 Option
FARRELL STEPHEN C director director
Common Stock 5,000 $7.14 $35,700 Option
FARRELL STEPHEN C director director
Common Stock Options 5,000 $7.14 $35,700 Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 217,693 $147.43 $32,094,479 Sale
BROADWOOD PARTNERS, L.P. 10 percent owner 10 percent owner
Common Stock 47,571 $143.42 $6,822,633 Option
FARRELL STEPHEN C director director
Common Stock 5,000 $7.14 $35,700 Option
FARRELL STEPHEN C director director
Common Stock Options 5,000 $7.14 $35,700 Sale
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock 14,500 N/A N/A Option
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock 94,855 $10.08 $956,138 Sale
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock 94,855 $130.42 $12,370,989 Option
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock Options 32,355 $11.75 $380,171 Option
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock 14,500 N/A N/A Option
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock Options 14,500 N/A N/A Option
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock Options 32,355 N/A N/A Option
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock 94,855 $10.08 $956,138 Option
BARNES SCOTT D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 12,295 $26.55 $326,469 Option
BARNES SCOTT D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock Options 12,295 $26.55 $326,469 Option
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock 5,145 $11.45 $58,885 Sale
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock 5,145 $128 $658,560 Option
BLICKENSDOERFER HANS-MARTIN officer: Sr. VP, Comm. Ops, Ch.. officer: Sr. VP, Comm. Ops, China
Common Stock Options 5,145 $11.45 $58,885 Option
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock 15,261 N/A N/A Sale
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock 15,261 N/A N/A Option
FRANCESE JAMES E officer: Sr. VP, Comm. Ops., NA, APAC officer: Sr. VP, Comm. Ops., NA..
Common Stock Options 15,261 N/A N/A Option
BARNES SCOTT D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 12,295 $26.55 $326,469 Option
BARNES SCOTT D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock Options 12,295 $26.55 $326,469