| Utility: TGF-beta superfamily type I and type II receptor heteromultimers and uses thereof Filling date: 8 Sep 2025 Issue date: 13 Sep 2022 | 5 Oct 2017 | 13 Sep 2022 |
| Utility: Compositions and methods for treating pulmonary hypertension Filling date: 8 Sep 2025 Issue date: 3 May 2022 | 4 Jun 2021 | 3 May 2022 |
| Utility: ALK4:ActRIIB heteromultimers and uses thereof Filling date: 8 Sep 2025 Issue date: 22 Mar 2022 | 27 Feb 2020 | 22 Mar 2022 |
| Utility: Variant ActRIIB proteins and uses thereof Filling date: 8 Sep 2025 Issue date: 8 Mar 2022 | 5 Oct 2017 | 8 Mar 2022 |
| Utility: Methods and compositions for treating ulcers Filling date: 8 Sep 2025 Issue date: 1 Mar 2022 | 18 Oct 2019 | 1 Mar 2022 |
| Utility: Compositions and methods for treating pulmonary hypertension Filling date: 8 Sep 2025 Issue date: 11 Jan 2022 | 25 Aug 2020 | 11 Jan 2022 |
| Utility: Single-arm type I and type II receptor fusion proteins and uses thereof Filling date: 8 Sep 2025 Issue date: 28 Dec 2021 | 28 May 2019 | 28 Dec 2021 |
| Utility: Method for treating myelofibrosis comprising administering a transforming growth factor beta type II receptor antagonist Filling date: 8 Sep 2025 Issue date: 21 Dec 2021 | 14 Dec 2017 | 21 Dec 2021 |
| Utility: Methods for treating anemia in a subject in need thereof Filling date: 8 Sep 2025 Issue date: 9 Nov 2021 | 19 Feb 2020 | 9 Nov 2021 |
| Utility: Methods for treating anemia in a subject in need thereof Filling date: 8 Sep 2025 Issue date: 2 Nov 2021 | 3 Mar 2020 | 2 Nov 2021 |
| Utility: Methods for treating anemia in a subject in need thereof Filling date: 8 Sep 2025 Issue date: 26 Oct 2021 | 19 Feb 2020 | 26 Oct 2021 |
| Utility: Method for promoting bone growth using activin-actriia antagonists Filling date: 8 Sep 2025 Issue date: 28 Sep 2021 | 3 Aug 2018 | 28 Sep 2021 |
| Utility: Methods for increasing red blood cell levels and treating ineffective erythropoiesis Filling date: 8 Sep 2025 Issue date: 21 Sep 2021 | 4 Nov 2016 | 21 Sep 2021 |
| Utility: Compositions and methods for treating pulmonary hypertension Filling date: 8 Sep 2025 Issue date: 20 Jul 2021 | 25 Aug 2020 | 20 Jul 2021 |
| Utility: Methods and compositions for reducing serum lipids Filling date: 8 Sep 2025 Issue date: 20 Jul 2021 | 7 Jun 2019 | 20 Jul 2021 |
| Utility: ALK7 binding proteins and uses thereof Filling date: 8 Sep 2025 Issue date: 13 Jul 2021 | 26 Nov 2019 | 13 Jul 2021 |
| Utility: ALK7:actriib heteromultimers and uses thereof Filling date: 8 Sep 2025 Issue date: 8 Jun 2021 | 18 Jan 2019 | 8 Jun 2021 |
| Utility: Transforming growth factor beta receptor type II fusion polypeptides Filling date: 8 Sep 2025 Issue date: 1 Jun 2021 | 3 May 2018 | 1 Jun 2021 |
| Utility: Methods of treating a fibrotic disorder by administering transforming growth factor beta receptor II fusion polypeptides Filling date: 8 Sep 2025 Issue date: 18 May 2021 | 30 Jan 2020 | 18 May 2021 |
| Utility: Methods of increasing muscle mass by administration of activin type 2 receptor antibodies Filling date: 8 Sep 2025 Issue date: 11 May 2021 | 22 Apr 2019 | 11 May 2021 |
| Utility: Method for treating a muscle-related disorder with follistatin-related fusion proteins Filling date: 8 Sep 2025 Issue date: 11 May 2021 | 19 Apr 2018 | 11 May 2021 |
| Utility: Methods of treating a sclerotic disorder by administering a transforming growth factor beta receptor type II fusion polypeptide Filling date: 8 Sep 2025 Issue date: 20 Apr 2021 | 24 Apr 2019 | 20 Apr 2021 |
| Utility: Endoglin polypeptides and uses thereof Filling date: 8 Sep 2025 Issue date: 20 Apr 2021 | 28 Feb 2018 | 20 Apr 2021 |
| Utility: Compositions and methods for treating pulmonary hypertension Filling date: 8 Sep 2025 Issue date: 13 Apr 2021 | 25 Aug 2020 | 13 Apr 2021 |
| Utility: Methods for screening compounds for increasing thermogenic adipocytes Filling date: 8 Sep 2025 Issue date: 6 Apr 2021 | 12 Jun 2019 | 6 Apr 2021 |
| Utility: Methods of increasing sarcolemmal utrophin Filling date: 8 Sep 2025 Issue date: 6 Apr 2021 | 15 Mar 2017 | 6 Apr 2021 |
| Utility: Methods and compositions for treatment of disorders with follistatin polypeptides Filling date: 8 Sep 2025 Issue date: 23 Mar 2021 | 12 Jun 2018 | 23 Mar 2021 |
| Utility: Compositions and methods for treating pulmonary hypertension Filling date: 8 Sep 2025 Issue date: 16 Mar 2021 | 25 Aug 2020 | 16 Mar 2021 |
| Utility: ALK4.ActRIIB heteromultimers Filling date: 8 Sep 2025 Issue date: 2 Mar 2021 | 5 Oct 2017 | 2 Mar 2021 |
| Utility: TGF-beta superfamily type I and type II receptor heteromultimers and uses thereof Filling date: 8 Sep 2025 Issue date: 2 Feb 2021 | 18 Jan 2019 | 2 Feb 2021 |
| Utility: Combined use of GDF traps and erythropoietin receptor activators to increase red blood cell levels Filling date: 8 Sep 2025 Issue date: 12 Jan 2021 | 19 Feb 2020 | 12 Jan 2021 |
| Utility: Combined use of GDF traps and erythropoietin receptor activators to increase red blood cell levels Filling date: 8 Sep 2025 Issue date: 10 Nov 2020 | 19 Feb 2020 | 10 Nov 2020 |
| Utility: Combined use of gdf traps and erythropoietin receptor activators to increase red blood cell levels Filling date: 8 Sep 2025 Issue date: 10 Nov 2020 | 19 Feb 2020 | 10 Nov 2020 |
| Utility: Methods and compositions for increasing red blood cells Filling date: 8 Sep 2025 Issue date: 10 Nov 2020 | 24 May 2019 | 10 Nov 2020 |
| Utility: Methods for treating myelodysplastic syndromes and sideroblastic anemias Filling date: 8 Sep 2025 Issue date: 10 Nov 2020 | 5 Dec 2018 | 10 Nov 2020 |
| Utility: Methods for treatment of charcot-marie-tooth disease with follistatin polypeptides Filling date: 8 Sep 2025 Issue date: 8 Sep 2020 | 18 May 2018 | 8 Sep 2020 |
| Utility: ALK4:ActRIIB heteromultimers and uses thereof Filling date: 8 Sep 2025 Issue date: 11 Aug 2020 | 12 Oct 2018 | 11 Aug 2020 |
| Utility: Compositions and methods for treating pulmonary hypertension Filling date: 8 Sep 2025 Issue date: 28 Jul 2020 | 14 Jul 2017 | 28 Jul 2020 |
| Utility: Compositions and methods for treating pulmonary hypertension Filling date: 8 Sep 2025 Issue date: 30 Jun 2020 | 4 Apr 2018 | 30 Jun 2020 |
| Utility: Combined use of GDF traps and erythropoietin receptor activators to increase red blood cell levels Filling date: 8 Sep 2025 Issue date: 23 Jun 2020 | 11 Oct 2018 | 23 Jun 2020 |
| Utility: Methods for treating pulmonary hypertension with a TGF-beta type II receptor-FC fusion protein Filling date: 8 Sep 2025 Issue date: 16 Jun 2020 | 21 Nov 2014 | 16 Jun 2020 |
| Utility: Methods and compositions using GDF15 polypeptides for increasing red blood cells Filling date: 8 Sep 2025 Issue date: 31 Mar 2020 | 29 Oct 2015 | 31 Mar 2020 |
| Utility: Methods for treating vascular eye disorders with actrii antagonists Filling date: 8 Sep 2025 Issue date: 4 Feb 2020 | 23 Nov 2016 | 4 Feb 2020 |
| Utility: ALK7 binding proteins and uses thereof Filling date: 8 Sep 2025 Issue date: 10 Dec 2019 | 21 Apr 2017 | 10 Dec 2019 |
| Utility: Methods for treating ulcers in a hemoglobinopathy anemia with a soluble actRIIB polypeptide Filling date: 8 Sep 2025 Issue date: 26 Nov 2019 | 21 Nov 2017 | 26 Nov 2019 |
| Utility: Methods of identifying ActRIIB variants Filling date: 8 Sep 2025 Issue date: 13 Aug 2019 | 27 Oct 2016 | 13 Aug 2019 |
