Option
FARFEL GAIL M officer: EVP/Chief Development Officer officer: EVP/Chief Development ..
Common Stock 7,000 $13.96 $97,720 Purchase
PERCEPTIVE ADVISORS LLC 10 percent owner 10 percent owner
Common Stock 100,000 $52 $5,200,000 Sale
FARFEL GAIL M officer: EVP/Chief Development Officer officer: EVP/Chief Development ..
Common Stock 7,000 $52.79 $369,495 Option
FARFEL GAIL M officer: EVP/Chief Development Officer officer: EVP/Chief Development ..
Common Stock 7,000 $13.96 $97,720 Option
FARFEL GAIL M officer: EVP/Chief Development Officer officer: EVP/Chief Development ..
Stock Option (Right to Buy) 7,000 $13.96 $97,720 Option
FARFEL GAIL M officer: EVP/Chief Development Officer officer: EVP/Chief Development ..
Stock Option (Right to Buy) 5,000 $13.96 $69,800 Option
FARFEL GAIL M officer: EVP/Chief Development Officer officer: EVP/Chief Development ..
Common Stock 5,000 $13.96 $69,800 Sale
FARFEL GAIL M officer: EVP/Chief Development Officer officer: EVP/Chief Development ..
Common Stock 5,118 $45 $230,310 Option
GARNER CAM L director director
Stock Option (Right to Buy) 218 $28 $6,104 Option
GARNER CAM L director director
Common Stock 218 $28 $6,104 Sale
GARNER CAM L director director
Common Stock 218 $28 $6,104 Option
HAWLEY ROGER director director
Stock Option (Right to Buy) 27,760 $16.61 $461,038 Option
HAWLEY ROGER director director
Common Stock 27,760 $16.61 $461,038 Sale
HAWLEY ROGER director director
Common Stock 27,760 $44.65 $1,239,428 Option
BOCK LOUIS C director director
Common Stock 24,716 $21.61 $534,113 Option
HAWLEY ROGER director director
Stock Option (Right to Buy) 7,240 $28 $202,720 Option
HAWLEY ROGER director director
Common Stock 7,240 $28 $202,720 Option
BOCK LOUIS C director director
Stock Option (Right to Buy) 218 $28 $6,104 Sale
BOCK LOUIS C director director
Common Stock 24,716 $44.84 $1,108,142 Sale
HAWLEY ROGER director director
Common Stock 7,240 $28 $202,720 Purchase
GALER BRADLEY S. officer: EVP/Chief Medical Officer officer: EVP/Chief Medical Offi..
Common Stock 1,346 $36.59 $49,245 Option
HAWLEY ROGER director director
Common Stock 63,203 $36.84 $2,328,462 Sale
HAWLEY ROGER director director
Common Stock 44,741 $36.84 $1,648,303 Option
HAWLEY ROGER director director
Stock Option (Right to Buy) 63,203 $36.84 $2,328,462 Sale
HAWLEY ROGER director director
Common Stock 11,797 $37.02 $436,701 Option
HAWLEY ROGER director director
Common Stock 11,797 $37.02 $436,701 Option
HAWLEY ROGER director director
Stock Option (Right to Buy) 11,797 $37.02 $436,701 Option
HAWLEY ROGER director director
Stock Option (Right to Buy) 36,370 $29.28 $1,064,914 Option
HAWLEY ROGER director director
Common Stock 56,370 $31.06 $1,750,852 Sale
HAWLEY ROGER director director
Common Stock 15,000 $15.04 $225,600 Purchase
PERCEPTIVE ADVISORS LLC 10 percent owner 10 percent owner
Common Stock 300,000 $37.5 $11,250,000 Purchase
PERCEPTIVE ADVISORS LLC 10 percent owner 10 percent owner
Common Stock 222,055 $34.89 $7,748,165 Purchase
PERCEPTIVE ADVISORS LLC 10 percent owner 10 percent owner
Common Stock 175,653 $14.45 $2,538,186 Purchase
TANNENBAUM RENEE P director director
Common Stock 5,000 $11 $55,000 Purchase
HAWLEY ROGER director director
Common Stock 20,000 $13.74 $274,860 Purchase
TANNENBAUM RENEE P director director
Common Stock 5,000 $15.4 $77,000 Purchase
HAWLEY ROGER director director
Common Stock 50,000 $1.59 $79,500 Purchase
HAWLEY ROGER director director
Common Stock 140,000 $1.31 $183,680 Purchase
GARNER CAM L director director
Common Stock 30,000 $1.66 $49,740 Sale
RHOADS ANN D officer: EVP, CFO, Treasurer & Sec. officer: EVP, CFO, Treasurer & ..
Common Stock 1,483 $2.01 $2,987 Sale
FARR STEPHEN J director, officer: President and CEO director, officer: President an..
Common Stock 1,612 $2.01 $3,247 Sale
SHIVELY RICHARD SCOTT officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Stock 1,483 $2.01 $2,987 Sale
HAWLEY ROGER director director
Common Stock 1,934 $2.01 $3,895 Sale
FARR STEPHEN J director, officer: President and CEO director, officer: President an..
Common Stock 19,288 $2.1 $40,543 Sale
SHIVELY RICHARD SCOTT officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Stock 17,746 $2.1 $37,302 Sale
RHOADS ANN D officer: EVP, CFO, Treasurer & Sec. officer: EVP, CFO, Treasurer & ..
Common Stock 17,746 $2.1 $37,302 Sale
HAWLEY ROGER director director
Common Stock 23,144 $2.1 $48,649 Purchase
SHIVELY RICHARD SCOTT officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Stock 67,000 $2.75 $184,250 Purchase
ROBINSON CYNTHIA Y officer: Chief Development Officer officer: Chief Development Offi..
Common Stock 50,000 $1.17 $58,500 Purchase
RHOADS ANN D officer: EVP, CFO, Treasurer & Sec. officer: EVP, CFO, Treasurer & ..
Common Stock 17,500 $1.19 $20,825